Question 1

strain of bacteria containing F? factor genes is called a

Accepted Answer

A)   monozygote.
B)   heterozygote.
C)   homozygote.
D)   merozygote.
E)   hemizygote.F) B) and C)
G) B) and E)

Question 2

Which of the following occurs in E. coli when lactose is absent from its environment?

Accepted Answer

A)   Large amounts of b-galactosidase, lactose permease, and galactoside transacetylase are made.
B)   Trace amounts of b-galactosidase, lactose permease, and galactoside transacetylase are made.
C)   No b-galactosidase, lactose permease, and galactoside transacetylase is made.
D)   The lac operon is induced.
E)   Polycistronic mRNA levels would be very high.F) A) and E)
G) A) and C)

Question 3

Which of the following does NOT occur during transcriptional regulation in eukaryotes?

Accepted Answer

A)   Chromatin is converted to the closed conformation.
B)   The gene must be transcribed.
C)   The RNA must be processed and exported from the nucleus.
D)   The protein must be made via translation.
E)   Chromatin is converted to the open conformation.F) A) and B)
G) All of the above

Question 4

Once the lac repressor binds to the lac operator site, RNA polymerase is prevented from transcribing which genes?

Accepted Answer

A)   galactosidase gene
B)   regulatory gene
C)   galactoside transacetylase gene
D)   galactosidase and galactoside transacetylase genes
E)   galactosidase and regulatory genesF) All of the above
G) B) and C)

Question 5

Alternative versions of proteins often have similar functions.

Accepted Answer

A) True 
 B)False  True

Question 6

Which of the following could alter the level of expression of a gene?

Accepted Answer

A)   an increase in environmental temperature
B)   an increase in salinity
C)   exposure to UV radiation
D)   presence of a particular energy substrate
E)   All of the choices are correct.F) A) and B)
G) A) and C)

Question 7

The lac operator site within the lac operon is an example of which of the following?

Accepted Answer

A)   cis-acting element
B)   para-acting element
C)   trans-acting element
D)   inter-acting element
E)   contra-acting elementF) B) and D)
G) A) and B) A

Question 8

Which of the following statements is TRUE of small effector molecules?

Accepted Answer

A)   Small effector molecules cause a conformational change in a regulatory protein.
B)   Small effector molecules can prevent a repressor from binding a gene region.
C)   Small effector molecules regulate gene transcription.
D)   Small effector molecules regulate gene transcription by binding a regulatory protein.
E)   All of the choices are correct.F) C) and E)
G) A) and D) D

Question 9

Which of the following is TRUE of the mediator protein complex in eukaryotes?

Accepted Answer

A)   Mediator facilitates interactions between RNA polymerase II and regulatory transcription factors.
B)   Mediator controls the rate at which RNA polymerase transcribes mRNA.
C)   Mediator partially wraps around RNA polymerase and the general transcription factors.
D)   Mediator is composed of several proteins.
E)   All of the choices are correct.F) A) and B)
G) A) and C)

Question 10

Which of the following is NOT true of the glucocorticoid receptor?

Accepted Answer

A)   The receptor contains a nuclear localization signal (NLS) .
B)   When bound to glucocorticoids, the receptors will bind covalently and irreversibly to each other to form dimers.
C)   Glucocorticoid receptor dimers bind glucocorticoid response elements (GREs) .
D)   Binding of glucocorticoid receptor dimers to GREs activates the transcription of the adjacent gene.
E)   The receptor contains a binding domain for glucocorticoids.F) B) and E)
G) A) and C)

Question 11

A cis-effect is a form of gene regulation that can occur between two DNA segments that are not physically adjacent.

Accepted Answer

A) True 
 B)False

Question 12

Which of the following occurs when allolactose levels increase in E. coli?

Accepted Answer

A)   Transcription of genes within the lac operon increases.
B)   Transcription of genes within the lac operon decreases.
C)   Transcription of genes within the lac operon does not change.
D)   E. coli cells replicate rapidly.
E)   The tryptophan operon becomes more active.F) None of the above
G) A) and D)

Question 13

Which of the following protein(s)  does NOT play a role in initiating transcription in eukaryotes?

Accepted Answer

A)   general transcription factors
B)   transposase
C)   RNA polymerase II
D)   mediator
E)   general transcription factors and RNA polymerase IIF) A) and C)
G) B) and E)

Question 14

Some genes such as that for b-actin are expressed at relatively constant levels in tissues regardless of variations in the animal's condition. What do we call this type of gene?

Accepted Answer

A)   transposable element
B)   steady state gene
C)   constitutive gene
D)   recombinant gene
E)   multifunctional geneF) A) and B)
G) A) and C)

Question 15

Which of the following is NOT a motif structure commonly found in transcription factor proteins?

Accepted Answer

A)   helix-turn-helix motif
B)   helix-loop-helix motif
C)   zinc finger motif
D)   arginine helix-loop-zipper motif
E)   leucine zipper motifF) B) and C)
G) D) and E)

Question 16

Why is the operon arrangement of genes beneficial to certain bacteria?

Accepted Answer

A)   It allows for the differential regulation of individual genes that encode proteins with a common function.
B)   It allows the coordinated regulation of a group of genes that encode proteins with a common function.
C)   It allows the separate regulation of individual genes that encode proteins with different functions.
D)   It allows the coordinated regulation of a group of genes that encode proteins with different functions.
E)   It allows for coordinated regulation of a group of proteins involved in numerous cellular activities.F) A) and E)
G) None of the above

Question 17

Jacob, Monod, and Pardee constructed a mutant strain of E. coli that carried a lacI-gene mutation (encodes the lac repressor) . Which is TRUE of this mutant strain?

Accepted Answer

A)   Trancription of the lac operon is repressed.
B)   Trancription of the lac operon does not change.
C)   The lac operon is constitutively expressed.
D)   Nonfunctional proteins are produced.
E)   The lac operon is constitutively expressed and nonfunctional proteins are producedF) C) and E)
G) C) and D)

Question 18

RNA polymerase can bind to the promoter region of the DNA even when the lac repressor is bound to the operator site.

Accepted Answer

A) True 
 B)False

Question 19

Which of the following are points of control for gene expression in eukaryotes?

Accepted Answer

A)   RNA processing
B)   translation
C)   transcription
D)   post-translational
E)   All of the choices are correct.F) A) and B)
G) A) and C)

Question 20

Where is the response element found in eukaryotic genes?

Accepted Answer

A)   10 to 20 base pairs downstream from the transcriptional start site
B)   50 to 100 base pairs downstream from the transcriptional start site
C)   50 to 100 base pairs upstream from the transcriptional start site
D)   10 to 20 base pairs upstream from the TATA box
E)   500 to 10,000 base pairs from the enhancer siteF) A) and B)
G) B) and E)

Exam 13: Gene Regulation

strain of bacteria containing F? factor genes is called a

Correct AnswerverifiedShow Answer

Which of the following occurs in E. coli when lactose is absent from its environment?

Correct AnswerverifiedShow Answer

Which of the following does NOT occur during transcriptional regulation in eukaryotes?

Correct AnswerverifiedShow Answer

Once the lac repressor binds to the lac operator site, RNA polymerase is prevented from transcribing which genes?

Correct AnswerverifiedShow Answer

Alternative versions of proteins often have similar functions.

Correct AnswerverifiedTrue

Which of the following could alter the level of expression of a gene?

Correct AnswerverifiedShow Answer

The lac operator site within the lac operon is an example of which of the following?

Correct AnswerverifiedA

Which of the following statements is TRUE of small effector molecules?

Correct AnswerverifiedD

Which of the following is TRUE of the mediator protein complex in eukaryotes?

Correct AnswerverifiedShow Answer

Which of the following is NOT true of the glucocorticoid receptor?

Correct AnswerverifiedShow Answer

A cis-effect is a form of gene regulation that can occur between two DNA segments that are not physically adjacent.

Correct AnswerverifiedShow Answer

Which of the following occurs when allolactose levels increase in E. coli?

Correct AnswerverifiedShow Answer

Which of the following protein(s) does NOT play a role in initiating transcription in eukaryotes?

Correct AnswerverifiedShow Answer

Some genes such as that for b-actin are expressed at relatively constant levels in tissues regardless of variations in the animal's condition. What do we call this type of gene?

Correct AnswerverifiedShow Answer

Which of the following is NOT a motif structure commonly found in transcription factor proteins?

Correct AnswerverifiedShow Answer

Why is the operon arrangement of genes beneficial to certain bacteria?

Correct AnswerverifiedShow Answer

Jacob, Monod, and Pardee constructed a mutant strain of E. coli that carried a lacI-gene mutation (encodes the lac repressor) . Which is TRUE of this mutant strain?

Correct AnswerverifiedShow Answer

RNA polymerase can bind to the promoter region of the DNA even when the lac repressor is bound to the operator site.

Correct AnswerverifiedShow Answer

Which of the following are points of control for gene expression in eukaryotes?

Correct AnswerverifiedShow Answer

Where is the response element found in eukaryotic genes?

Correct AnswerverifiedShow Answer

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